Olay Regenerist Wrinkle Revolution Complex

A new formula is added in July 2011 to the Olay Regenerist range : Regenerist Wrinkle Revolution Complex.

Olay Regenerist Wrinkle Revolution Complex

This new addition in the Olay Regenerist range is not such a “revolution” in terms of technology : the structure of the formula is quite classical, and the active ingredients and the “light-manipulating” ingredients are well known and already used in existing skincare products. However, it tries a new positioning for a skincare product : it clearly emphasizes the optical properties, even before the “biological” properties of the formula (“light-manipulation” before moisturization). It is clearly positionned as a skincare, not as a make-up, but in the recommended routine, it shall be used as a “step 3”, after the cleanser and the moisturizer, as a “moisturizer/primer”, a smart way to broaden an already broad skincare range.

Active ingredients / Claims :

The formula contains several active ingredients. Among them, 7 are claimed :

Niacinamide : Vitamin B3, the classical active ingredient of Olay, present in almost every cream / serum of the P&G skincare brand.

Panthenol : Pro-vitamin B5

Palmitoyl Pentapeptide-4, named “Amino-acid” or “Pal-KTTKS”. It is a star ingredient of the Olay Regenerist range, for which the mother company of Olay, Procter & Gamble, has made a specific brochure detailing its properties. Pal-KTTKS stands for “Palmitoyl”, a fatty chain, attached to 5 amino-acids : Lysine-Threonine-Threonine-Lysine-Serine (Lysine is shorten “K”, Threonine is shorten “T” and Serine is shorten “S” in Biology).

Here is an interesting story about this active ingredient. This pentapeptide has been originally designed by Sederma, a french supplier of active ingredients for the cosmetic industry, and sold under now quite famous the tradename “Matrixyl”. Sederma owns a patent registered in 1999 on this active ingredient. This Sederma patent protects the structure and the use of peptides like Pal-KTTKS in cosmetic and dermatological composition, quite a strong patent.

However, it is now an exclusive ingredient of the P&G Company, thanks to another patent from P&G : in order to stop anyone from using Matrixyl, which P&G certainly found very interesting, it registered another patent in 2000. This one protects the use of Matrixyl with “a safe and effective amount of at least one additional skin care active selected from the group consisting of desquamatory actives, anti-acne actives, vitamin B3 compounds, retinoids, di-, tri-, and tetra- peptides and derivatives thereof, hydroxy acids, radical scavengers, chelators, anti-inflammatory agents, topical anesthetics, tanning actives, skin lightening agents, anti-cellulite agents, flavonoids, antimicrobial actives, skin healing agents, antifungal actives, farnesol, phytantriol, allantoin, glucosamine, and mixtures thereof” in “a dermatologically acceptable carrier“, that is to say : any composition associating Matrixyl with another active ingredient !!! That is tricky, but it is how companies use patents to protect their business ! P&G is thus the only one to be able to use Sederma’s Matrixyl !

But Sederma has not lost everything in this trick : first, it can still make money with its Palmitoyl Pentapeptide-4 since it can sell it to P&G, but only to P&G. Secondly, Sederma is the only owner of the “Matrixyl” tradename, and P&G cannot use it, unless Sederma gives its agreement. Maybe that is why P&G uses “Pal-KTTKS” in its communications. And thirdly, has a revenge, Sederma has developed a new Matrixyl, “Matrixyl 3000“, made this time of two peptides, better patent-protected then the first version, and this time available to everyone.

Carnosine : also named “amino-acid”. It could be Symrise Dragosine, claimed to have anti-aging properties (anti-oxydant, reactive oxygen species scavenger, chelating agent with heavy metals, reactive carbonyl species scavenger, Advanced Glycation End (AGE) products quencher, cross-linking of macromolecules preventor). It is claimed to have the ability to decrease the formation of DNA-protein cross-linking.
like collagen

Tocopheryl Acetate : named “Vitamin E”, it is more precisely Vitamin E Acetate.

Camellia Sinensis Leaf Extract : Green Tea leaf extract, very classical active ingredient in skincare products. It has several properties, mainly due to the polyphenol Epigallocatechin Gallate (EGCG) it contains. Green Tea leaf extract would thus have anti-carcinogenic, antioxidant, anti-inflammatory properties, and would quench UV induced free radicals.

Yeast Extract

Apart from these claimed active ingredients, the Olay Regenerist Wrinkle Revolution Complex also contains :


Presented as a “wrinkle treatment”, Olay Regenerist Wrinkle Revolution Complex formula is claimed to “hydrate to reduce the appearance of deep lines in just 14 days”

But in the communication on this new Regenerist formula, the emphasize is not put on these active ingredients, but on the “light-manipulating” powders and silicons it contains :

– Polyethylene beads

– Aluminum Starch Octenylsuccinate (Akzo Nobel’s Dry Flo)

– Polymethylsilsesquioxane (Momentive Tospearl Microspheres, described as mono-dispersed micro-fine spherical cross-linked siloxane particules, providing soft focus effect for reduced appearance of fine lines and wrinkles)

– Dimethicone Crosspolymer, a silicone elastomer

They are presented as “advanced micro-fillers and light-diffusing particles [that] smooth the look of fine lines”, and indeed, due to their physical properties, these ingredients have the ability to disperse and diffuse light. It is has if fine lines were blurred.

The combination of the active ingredients with the “light-manipulating” raw materials results in a formula claimed to “dramatically” reduced wrinkle appearence “after just 1 application”.

Technology / Formula structure :

Olay Regenerist Wrinkle Revolution Complex

O/W emulsion, emulsified with PEG-100 Stearate, thickened with Acrylamide/Sodium Acryloyldimethyltaurate Copolymer and Ammonium Polyacrylate.

Ammonium Polyacrylate could be Covacryl VIP from LCW/Sensient, claimed to form clear gels with surfactants, and being compatible with alcohol.

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer can be found in Seppic catalog under the tradename “Simulgel 600”. However, Simulgel 600 also contains Isohexadecane and Polysorbate 80. Indeed, it is a ready-to-use liquid polymer prepared as a W/O emulsion, that thickens when poured in the preparation during manufacturing. Put on the market by Seppic with Sepigel 305 (Polyacrylamide (and) C13-14 Isoparaffin (and) Laureth-7), this technology is a very convenient to formulate polymers, and has been now adopted by several other manufacturers. But here in the Olay formula, no Isohexadecane nor Polysorbate 80 is used. Two ingredients typical of Sepigel 305 (C13-14 Isoparaffin and Laureth-7) are present. One can suppose that they are associated with Acrylamide/Sodium Acryloyldimethyltaurate Copolymer as a raw material sold to cosmetic manufacturers.

The oil phase is made of silicones – Cyclopentasiloxane, Dimethicone.

The aqueous phase contains Glycerin and Propylene Glycol as humectants.

The formula contains several “light-manipulating” raw materials : powders – Polyethylene beads, Aluminum Starch Octenylsuccinate (Akzo Nobel’s Dry Flo), Polymethylsilsesquioxane (Momentive Tospearl Microspheres, described as mono-dispersed micro-fine spherical cross-linked siloxane particules, providing soft focus effect for reduced appearance of fine lines and wrinkles) and Titanium Dioxide – and a silicone crosspolymer – Dimethicone Crosspolymer.

Preservatives system :

The formula is protected against microbiological growth by DMDM Hydantoin, an antimicrobial formaldehyde releaser preservative, and Iodopropynyl Butylcarbamate, helped with Disodium EDTA. The pH of the formula is corrected with Citric Acid.

Ingredients :

Propylene Glycol
Aluminum Starch Octenylsuccinate
Dimethicone Crosspolymer
Palmitoyl Pentapeptide-4
Tocopheryl Acetate
Camellia Sinensis Leaf Extract
Yeast Extract
Disodium EDTA
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
C13-14 Isoparaffin
PEG-100 stearate
DMDM Hydantoin
Iodopropynyl Butylcarbamate
Ammonium Polyacrylate
Citric Acid
Titanium dioxide

By A.B.

One thought on “Olay Regenerist Wrinkle Revolution Complex”
  1. Thanks so much for post this article.
    I was very interesting, specially the story about Matrixyl.

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